Kuan EC; Peng KA; Thompson CF; Suh JD; Wang MB
Hereditary hemorrhagic telangiectasia (HHT) is an affiliated vascular ataxia which manifests as recurrent, episodic, and potentially debilitating epistaxis. In this study, we aim to (1) characterize baseline sinonasal affection for HHT patients and to (2) assay changes in sinonasal affection afore and afterwards laser surgical analysis for HHT. We performed a attendant blueprint analysis of sinonasal aftereffect test-22 (SNOT-22) array afore and afterwards one or added laser surgical treatments for HHT-related epistaxis amid January 1, 2010 and December 1, 2015 at a tertiary bookish medical centermost with an HHT Foundation-approved Centermost of Excellence. Preoperative and all after postoperative SNOT-22 array (short-term, <45 days and long-term, ≥45 days) were compared. Twenty after HHT patients underwent 51 laser surgeries for alternate epistaxis. Mean preoperative, concise postoperative, and abiding postoperative SNOT-22 array were 34.6 ± 5.4, 33.9 ± 5.5, and 18.8 ± 4.6, respectively. When allegory subcategory scores, there was a cogent advance in the rhinologic area from concise to abiding postoperatively (13.5 vs. 7.3; p = 0.004), in the non-rhinologic otolaryngic area from concise to abiding postoperatively (2.8 vs. 1.7; p = 0.014), and in the cerebral area from preoperative and concise postoperative to abiding postoperatively (12.2 and 10.0 vs. 6.0; p = 0.015 and 0.01, respectively). Afterward laser anaplasty for HHT-related epistaxis, patients' rhinologic affection worsened on the abbreviate run postoperatively but bigger over time. The capital account of laser analysis appears to be abiding advance in cerebral factors. This abstraction already afresh underscores the important role of the otolaryngologist in managing sinonasal manifestations of HHT.
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
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